The Balance of Nitric Oxide and Peroxynitrite in the Heart During Organ Preservation
The culmination of this research was to develop and optimize a solution for long-term cardiac preservation for transplantation. This optimal solution was created using Celsior solution with the addition of several compounds including: L-arginine, sepiapterin, and BH4. This new storage solution was able to maintain hemostasis in the L-arginine/NO/ONOO- pathway by the storage time beyond 10 hours, increasing the NO/ONOO - ratio and by supporting the eNOS enzyme activity in stored hearts.75 Figure 2-1: Rat heart left ventricle (not drawn to scale). Slices of left ... Original entire heart diagram adapted from http://www.biosbcc.net/b100cardio/htm/ heartant.htm.164 . ... 88 Figure 2-4: Schematic diagram of the NO nanosensor.
| Title | : | The Balance of Nitric Oxide and Peroxynitrite in the Heart During Organ Preservation |
| Author | : | Allyson Jill Kozak |
| Publisher | : | ProQuest - 2007 |
You must register with us as either a Registered User before you can Download this Book. You'll be greeted by a simple sign-up page.
Once you have finished the sign-up process, you will be redirected to your download Book page.
How it works:- 1. Register a free 1 month Trial Account.
- 2. Download as many books as you like (Personal use)
- 3. Cancel the membership at any time if not satisfied.
